The College of Pharmacy discussed today, Thursday, 6/8/2023

Master’s thesis tagged: Role of genetic polymorphism of cyp2c19 on therapeutic response of famoxifen in Iraqi breast cancer Women

Submitted by the student: (Zahraa Hadi Al-Musawi) as part of the requirements for obtaining a master’s degree in the specialty of drugs and toxins

The thesis included a study on breast cancer, which is considered a global health problem affecting the breast. This study was conducted in the laboratories of the College of Pharmacy at the University of Karbala, as well as the Imam Hussein Medical Center / Oncology Center in Karbala.

The study was conducted on a total of 100 Iraqi women, aged between 45-65 years, who had breast cancer positive for estrogen and/or progesterone receptors and took tamoxifen tablets 20 mg daily for at least three months without any disease.

The study concluded that the genetic variation in the CYP2C19 phase metabolizing enzyme may contribute to the variation in the response to tamoxifen treatment in a sample of Iraqi breast cancer.