⭕️Vitamin C is a water-soluble vitamin, antioxidant, and essential co-factor for collagen biosynthesis, carnitine and catecholamine metabolism, and dietary iron absorption.

⭕️Dose &dosage form :

100,250,500mg tablets 

Injectable sol:250mg/ml,500mg/ml

Oral sol:100mg/ml

⭕️Indication:

Vitamin C is indicated to prevent and treat scurvy

helping to protect cells and keeping them healthy. maintaining healthy skin, blood vessels, bones and cartilage. helping with wound healing.

⭕️Mechanism of Action

Absorption is through an energy-dependent process that has two mechanisms: simple diffusion and active transport. Two transporters are involved: SVCTs (sodium-dependent vitamin C transporters) and hexose transporters. The site for absorption is the distal small intestine and is regulated by renal excretion. Usual dietary doses of up to 100 mg/day are almost completely absorbed

⭕️Adverse Effects

Adverse effects include headaches, flushing, nausea or vomiting, and dizziness (IV use). There are reports of migraine headaches with a daily dose of 6 g.

Significant amounts of vitamin C can increase the risk of kidney stones and elevate uric acid and oxalate because it acidifies the urine.

🛑References

Fenech M, Amaya I, Valpuesta V, Botella MA. Vitamin C Content in Fruits: Biosynthesis and Regulation. Front Plant Sci. 2018;9: