![التوليف ومضاد للجراثيم نشاط بعض جديد α-فينيل السنامويل Thiosemicarbazide وتبديل 5-α-فينيل Styryl-1،3،4-الترايازول-2-ثيول](https://i0.wp.com/pharmacy.uokerbala.edu.iq/wp/en/wp-content/uploads/sites/6/2014/10/pharmacy.uokerbala.edu.iq_images_adobe-pdf-logo.png?resize=35%2C35&ssl=1)
Synthesis And Antibacterial Activity Of Some New α-Phenylcinnamoyl Thiosemicarbazides And 5-Substituted-α-Phenylstyryl-1,3,4-Triazole-2-Thiols
Georg Y. Sarkis Ahmed S. Hamed
Department of chemistry Department of chemistry
College of Science College of Education for Women
Mustansiriya University University of Tikreet
Baghdad – Iraq Tikreet- Iraq
Abstract
A series of new derivatives of α-phenylcinnamoyl thiosemicarbazides have been synthesized and converted to 5-substituted- α-phenylstyryl-1,3,4-triazole-2-thiols.These compounds were screened for their antibacterial activity against Staphylococcus aureus ,Escherichia coli and pseudomonas aeruginosa. It was found that α- phenylcinnamoyl thiosemicarbazides were more active than triazoles againstStaphylococcus aureus and Escherichia coli.