Articles

Abstract De novo mutations in protein-coding genes are a well-established cause of developmental disorders1. However, genes known to be associated

Abstract Most deaths from cancer are explained by metastasis, and yet large-scale metastasis research has been impractical owing to the

Abstract Ageing is a degenerative process that leads to tissue dysfunction and death. A proposed cause of ageing is the

Abstract Although single-cell RNA sequencing studies have begun to provide compendia of cell expression profiles, it has been difficult to

Importance Gastroesophageal reflux disease (GERD) is defined by recurrent and troublesome heartburn and regurgitation or GERD-specific complications and affects approximately

Ageing of the population, together with population growth, has brought along an ample increase in the number of older individuals

Blood pressure (BP) in the office is often recorded without standardization of the technique of measurement. When office BP measurement

Abstract Objective In an era of increasing polypharmacy, adverse drug effects such as ototoxicity have significant public health implications. Despite

Abstract Evidence‐based management of analgesia and sedation in COVID‐19‐associated acute respiratory distress syndrome remains limited. Non‐guideline recommended analgesic and sedative

NEW YORK — December 17, 2020 — Both hyperglycaemia and hypoglycaemia were associated with poor outcomes in patients with coronavirus