The lecturer at the College of Pharmacy at the University of Karbala, Assistant Professor Dr. Salam Ahmed Abd, participated in the discussion of his doctoral thesis at the College of Science at the University of Karbala on the preparation of dendrimers and imidazole and the study of their biochemical and biological effectiveness.

The study presented by researcher Sawsan Khudair Abbas aimed to prepare organic polyamidation branched compounds, prepare heterocyclic compounds such as imidazoles, study their biochemical applications as anti-urine stones, and know their ability to inhibit the growth of stones, in addition to their applications as anti-diabetics and stabilize the sugar enzyme alpha-amylase. And alpha-glucosidase and its antibacterial effect and its effect on blood hemolysis.

The thesis included the preparation and diagnosis of highly branched dendrimers (PAMAM dendrimers) and imidazole derivatives (triimidazole and tetraimidazole), important organic compounds that play an important role in medicinal chemistry, as well as studying their properties in biochemical and biological applications. Some of the prepared compounds were subjected to anti-urinary stone activity and examined. Its anti-diabetic activity and anti-bacterial activity as well as hemolysis tests.

The study concluded that some of these compounds have the ability to inhibit the growth of stones and reduce their size, in addition to their ability to inhibit the enzymes responsible for the breakdown and rise of sugar, and have the ability to inhibit bacteria, and that some of these compounds do not affect the breakdown of blood through conducting blood tests.

The study recommended the need to conduct more tests in this area within the body to ensure their use as medicines in the future and to conduct other tests such as antioxidants and toxicity tests.