A doctoral thesis at the College of Science at the University of Karbala discussed the role of colibactin production in the development of intestinal inflammatory diseases.

The thesis submitted by researcher Hoda Najeh aimed to study the role of toxins from E. coli bacteria isolated from patients with ulcerative colitis and Crohn’s disease in the development of intestinal diseases in laboratory rats.

The thesis concluded that Crohn’s disease and ulcerative colitis affect women more than men, and that E. coli bacteria isolated from patients possess toxin-producing genes.

The thesis recommended conducting more studies on the E. coli bacteria and the other virulence factors it possesses and their role in the development of intestinal diseases.