Delayed initiation of remdesivir beneficial for COVID‐19, neutrophil-to-lymphocyte ratio predicts mortality in hospitalised patients with COVID-19, and arbidol monotherapy for COVID-19

In today’s DG Alert, we cover late initiation of remdesivir antiviral therapy in the successful treatment of a patient with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), neutrophil-to-lymphocyte ratio (NLR) as an independent risk factor for mortality in hospitalised patients with coronavirus…

COVID-19: Urea dissociation tests could help reduce SARS-CoV-2 IgM false-positives

22 April، 2020

NEW YORK — April 17, 2020 — Researchers have identified factors that lead to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) IgM false-positives. The findings are published in Journal of Clinical Microbiology. Qiang Wang, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan,…

NIH to launch public-private partnership to speed COVID-19 vaccine and treatment options

22 April، 2020

The National Institutes of Health and the Foundation for the NIH (FNIH) are bringing together more than a dozen leading biopharmaceutical companies, the Health and Human Services Office of the Assistant Secretary for Preparedness and Response, the Centers for Disease Control and…

Hypersensitivity of b- lactam antibiotics : Pharmaceutical chemistry point of view

Hypersensitivity of b- lactam antibiotics : Pharmaceutical chemistry point of view

28 January، 2018

b– Lactam is a group of antibiotic that includes penicillins ( such as ampicillin and amoxicillin) and cephalosporins such as cephalexin, cefuroxime, cefotaxime, and ceftriaxone). These antibiotics composed from semi-complex chemical structure contains an essential four member ring which is called b-…